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Even though the transport capacity of the renal cortex is huge, it is not infinite There are upper limits to the speed with which any given solute can be reabsorbed from the tubular lumen to capillary blood In certain situations, these limits are reached, with the consequence that more than the usual amount of solute is not reabsorbed (ie, left in the lumen to be passed on to the next nephron segment) In general, transport mechanisms can be classified by the properties of these limits as either (1) tubular maximum-limited (Tm) systems or (2) gradient-limited systems Tm systems reach an upper limit because the transporters moving the substance become saturated; any further increase in solute concentration does not increase the rate at which the substance binds to the transporter and thereafter moves through the membrane Gradient-limited systems reach an upper limit because the tight junctions are leaky, and any significant lowering of luminal concentration relative to the interstitium results in a leak back into the lumen as fast as the substance is transported out Thus, the upper rate for the Tmlimited system is a property of the transporter, whereas the upper rate of a gradient-limited system is a property of the permeability of the epithelial monolayer regardless of the maximal rate of the transport protein Let us explain Tm-limited systems using glucose as an example Glucose is present in plasma at a concentration of about 5 mmol/L (90 mg/dL) and is freely filtered It is reabsorbed by the transcellular route Glucose enters the epithelial cells across the apical membrane via a symporter with sodium (a member of the SGLT protein family) and exits across the basolateral membrane into the interstitium via a uniporter (a GLUT protein family member) Normally, all the filtered glucose is reabsorbed in the proximal tubule, with none remaining in the lumen to be passed on to the loop of Henle However, if the filtered load of glucose is abnormally high, the SGLT proteins upper limit for reabsorption is reached That upper limit is the tubular maximum, or Tm, for glucose It is the maximum rate at which the substance (glucose in this case) can be reabsorbed regardless of the luminal concentration Any increase in filtered load above the Tm, which for glucose. vb.net qr code generator free QR Code Bar Code Generator for VB . NET | Create ... - Barcode SDK
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eclipse birt qr code Nov 9, 2018 ยท How to Generate a QR Code [qr code generator] in Visual Basic .NET using QRCoder QRCoder ...Duration: 4:26 Posted: Nov 9, 2018 java read qr code from camera For example, if liquid titanium(IV) chloride (acidified with HCl) is electrolyzed by a current of 1000 amp for 2000 h, how many grams of titanium will be produced Answer: TiCl 4 ( l ) Ti( s) + 2Cl 2 ( g )( not necessary ) Ti 4+ + 4 e Ti ( necessary ) 1mole Ti 4 7 90 g Ti ( 2 000 h ) 3600 s 1 000 C 1mole e h 96485 C 4 mole e mol Ti s = 0 8936gTi Calculation of E cell also allows for the calculation of two other useful quantities the Gibbs free energy ( G ) and the equilibrium constant (K ) The Gibbs free energy is the best single thermodynamic indicator of whether a reaction will be spontaneous (review the Thermodynamics chapter) The Gibbs free energy for a reaction can be calculated from the E of the reaction using the following equation: G = nFE cell where F is Faraday s constant of 96,500 C/mol e = 96,500 J/V qr code vb.net library VB.NET QR Code Generator generate, create 2D barcode QR Code ...
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